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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRA2A
All Species:
26.67
Human Site:
Y132
Identified Species:
53.33
UniProt:
P08913
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08913
NP_000672.3
450
48957
Y132
C
A
I
S
L
D
R
Y
W
S
I
T
Q
A
I
Chimpanzee
Pan troglodytes
XP_521603
468
50335
R132
Y
N
L
K
R
T
P
R
R
I
K
A
I
I
I
Rhesus Macaque
Macaca mulatta
XP_001087738
450
49113
Y132
C
A
I
S
L
D
R
Y
W
S
I
T
Q
A
I
Dog
Lupus familis
XP_544018
622
67080
Y147
C
A
I
S
L
D
R
Y
W
S
I
T
Q
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q01338
450
48847
Y132
C
A
I
S
L
D
R
Y
W
S
I
T
Q
A
I
Rat
Rattus norvegicus
P22909
450
48921
Y132
C
A
I
S
L
D
R
Y
W
S
I
T
Q
A
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513049
394
43582
E120
Y
F
G
K
A
W
C
E
I
Y
L
A
L
D
V
Chicken
Gallus gallus
XP_426355
614
69002
Y310
C
A
I
S
L
D
R
Y
W
S
V
T
Q
A
V
Frog
Xenopus laevis
P24628
442
49720
M132
D
R
Y
T
A
V
A
M
P
M
L
Y
N
T
R
Zebra Danio
Brachydanio rerio
Q90WY4
388
43978
C114
T
A
S
I
T
H
L
C
A
I
S
L
D
R
Y
Tiger Blowfish
Takifugu rubipres
P53453
463
52101
T132
A
I
S
I
D
R
Y
T
A
V
A
M
P
M
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200819
471
53401
Y151
C
L
I
S
I
D
R
Y
C
S
I
T
R
P
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.6
96.4
58.5
N.A.
92.2
90.8
N.A.
45.5
43
33.3
60.4
32.6
N.A.
N.A.
N.A.
36
Protein Similarity:
100
86.1
96.6
62
N.A.
94
92.8
N.A.
53.1
51.2
50.6
70.6
49.4
N.A.
N.A.
N.A.
53
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
0
86.6
0
6.6
0
N.A.
N.A.
N.A.
66.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
13.3
100
13.3
6.6
6.6
N.A.
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
59
0
0
17
0
9
0
17
0
9
17
0
50
0
% A
% Cys:
59
0
0
0
0
0
9
9
9
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
59
0
0
0
0
0
0
9
9
0
% D
% Glu:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
59
17
9
0
0
0
9
17
50
0
9
9
59
% I
% Lys:
0
0
0
17
0
0
0
0
0
0
9
0
0
0
0
% K
% Leu:
0
9
9
0
50
0
9
0
0
0
17
9
9
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
9
0
9
0
9
0
% M
% Asn:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
9
0
9
0
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% Q
% Arg:
0
9
0
0
9
9
59
9
9
0
0
0
9
9
9
% R
% Ser:
0
0
17
59
0
0
0
0
0
59
9
0
0
0
0
% S
% Thr:
9
0
0
9
9
9
0
9
0
0
0
59
0
9
0
% T
% Val:
0
0
0
0
0
9
0
0
0
9
9
0
0
0
17
% V
% Trp:
0
0
0
0
0
9
0
0
50
0
0
0
0
0
0
% W
% Tyr:
17
0
9
0
0
0
9
59
0
9
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _